Validated potentiometric method for the determination of sulfacetamide sodium; application to its pharmaceutical formulations and spiked rabbit aqueous humor
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New Validated Potentiometric Determination of Vasodilator Pentoxifylline in its Pharmaceutical Formulations and Biological Fluids
The construction and performance characteristics of pentoxifylline selective electrodes were developed. Two types of electrodes: plastic membrane I and coated wire II were constructed based on the incorporation of pentoxifylline with phosphotungstic acid (PTA). The influence of membrane composition, kind of plasticizer, pH of the test solution, soaking time, and foreign ions on the electrodes w...
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Captopril, chemically know as 1-[(2S)-3mercapto-2-methylpropionyl]-L-proline, (CPT) is used therapeutically as an antihypertensive agent [11, 15], which is also prescribed for the treatment of congestive hart failure [6]. Several types of analytical procedures have been proposed for the analysis of captopril in pharmaceuticals formulations. These procedures include capillary electrophoresis [13...
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A poly (vinyl chloride) membrane electrode with dibutyl phthalate as plasticizer based on the fentanyl-phosphotungstate ion-association complex as ion-exchange site for the determination of fentanyl citrate in injections was developed. A linear response for 1 x 10(-5)-1 x 10(-2) mol dm(-3) drug with a slope of 55.9 +/- 0.4 mV per decade was established. The optimum pH range was 1-7. The lower d...
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Losartan, a highly effective blood pressure lowering agent, has been widely used for the treatment of hypertension. A fast and reliable method for the determination of losartan was highly desirable to support formulation screening and quality control. A first derivative UV spectroscopic method was developed for determination of losartan in the tablet dosage form. The first derivative spectrum r...
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Objective: The main objective of the present work is to develop a specific validated HPLC method for the determination of Meprobamate in bulk and pharmaceutical dosage forms. Method: A reverse phase HPLC method was developed using Bondapak C18 10 μm (3.9 x 300 mm) Capillary column was employed for investigation and mobile phase of composition Acetonitrile: Water in the ratio of 50:50 v/v at a f...
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ژورنال
عنوان ژورنال: Bulletin of Faculty of Pharmacy, Cairo University
سال: 2018
ISSN: 1110-0931
DOI: 10.1016/j.bfopcu.2018.08.002